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1

Comparison of in vitro toxicological effects of biomass smoke from different sources of animal dung

McCarthy, Claire E., Duffney, Parker F., Wyatt, Jeffrey D., Thatcher, Thomas H., Phipps, Richard P., Sime, Patricia J.

Journal:

Toxicology in Vitro

Year:

2017

Language:

english

File:

PDF, 2.00 MB

english, 2017

2

Prevention and treatment of bleomycin-induced pulmonary fibrosis with the lactate dehydrogenase inhibitor gossypol

Judge, Jennifer L., Nagel, David J., Owens, Kristina M., Rackow, Ashley, Phipps, Richard P., Sime, Patricia J., Kottmann, R. M., Ryffel, Bernhard

Journal:

Year:

2018

Language:

english

File:

PDF, 19.37 MB

english, 2018

3

Missing quality of life data in cancer clinical trials: serious problems and challenges

Jürg Bernhard, David F. Cella, Alan S. Coates, Lesley Fallowfield, Patricia A. Ganz, Carol M. Moinpour, Paola Mosconi, David Osoba, John Simes, Christoph Hürny

Journal:

Statistics in Medicine

Year:

1998

Language:

english

File:

PDF, 173 KB

english, 1998

4

A putative role for platelet-derived PPARγ in vascular homeostasis demonstrated by anti-PPARγ induction of bleeding, thrombocytopenia and compensatory megakaryocytopoiesis

Patricia J. Simpson-Haidaris, Kathryn E. Seweryniak, Sherry L. Spinelli, Tatiana M. Garcia-Bates, Thomas I. Murant, Stephen J. Pollock, Patricia J. Sime, Richard P. Phipps

Journal:

Journal of Biotechnology

Year:

2010

Language:

english

File:

PDF, 2.07 MB

english, 2010

5

Titration of non-replicating adenovirus as a vector for transducing active TGF-β1 gene expression causing inflammation and fibrogenesis in the lungs of C57BL/6 mice

G. Sakuntala Warshamana, Derek A. Pociask, Krishna J. Fisher, Jing-Yao Liu, Patricia J. Sime, Arnold R. Brody

Journal:

International Journal of Experimental Pathology

Year:

2002

Language:

english

File:

PDF, 27.38 MB

english, 2002

6

Determinants of initiation and progression of idiopathic pulmonary fibrosis

Robert Matthew KOTTMANN, Christopher M. HOGAN, Richard P. PHIPPS, Patricia J. SIME

Journal:

Year:

2009

Language:

english

File:

PDF, 331 KB

english, 2009

7

The mystery of transfusion-related acute lung injury

Neil Blumberg, Patricia J. Sime, Richard P. Phipps

Journal:

Transfusion (Wiley)

Year:

2011

Language:

english

File:

PDF, 56 KB

english, 2011

8

Asbestos-derived reactive oxygen species activate TGF-β1

Pociask, Derek A, Sime, Patricia J, Brody, Arnold R

Journal:

Laboratory Investigation

Year:

2004

Language:

english

File:

PDF, 304 KB

english, 2004

9

A novel ELISpot method for adherent cells

Chantal K. Turner, Timothy M. Blieden, Terry J. Smith, Steven E. Feldon, David C. Foster, Patricia J. Sime, Richard P. Phipps

Journal:

Journal of Immunological Methods

Year:

2004

Language:

english

File:

PDF, 954 KB

english, 2004

10

Mixed Lineage Kinase 3 deficiency delays viral clearance in the lung and is associated with diminished influenza-induced cytopathic effect in infected cells

Emily A. Desmet, Joseph A. Hollenbaugh, Patricia J. Sime, Terry W. Wright, David J. Topham, Andrea J. Sant, Toru Takimoto, Stephen Dewhurst, Sanjay B. Maggirwar

Journal:

Year:

2010

Language:

english

File:

PDF, 994 KB

english, 2010

11

Spatial-specific TGF-β1 adenoviral expression determines morphogenetic phenotypes in embryonic mouse lung

Jingsong Zhao, Patricia J. Sime, Pablo Bringas Jr., J. Denise Tefft, Sue Buckley, Ding Bu, Jack Gauldie, David Warburton

Journal:

European Journal of Cell Biology

Year:

1999

Language:

english

File:

PDF, 6.86 MB

english, 1999

12

The Aryl Hydrocarbon Receptor Ligand ITE Inhibits TGFβ1-Induced Human Myofibroblast Differentiation

Geniece M. Lehmann, Xia Xi, Ajit A. Kulkarni, Keith C. Olsen, Stephen J. Pollock, Carolyn J. Baglole, Shikha Gupta, Ann E. Casey, Krystel R. Huxlin, Patricia J. Sime, Steven E. Feldon, Richard P. Phip

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 2.34 MB

english, 2011

13

Lung-Targeted Overexpression of the NF-κB Member RelB Inhibits Cigarette Smoke–Induced Inflammation

David H. McMillan, Carolyn J. Baglole, Thomas H. Thatcher, Sanjay Maggirwar, Patricia J. Sime, Richard P. Phipps

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 1.69 MB

english, 2011

14

Lung fibroblast clones from normal and fibrotic subjects differ in hyaluronan and decorin production and rate of proliferation

Gunilla Westergren-Thorsson, Patricia Sime, Manel Jordana, Jack Gauldie, Bengt Särnstrand, Anders Malmström

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2004

Language:

english

File:

PDF, 247 KB

english, 2004

15

Eastern oysters (Crassostrea virginica) as an indicator for restoration of Everglades Ecosystems

Aswani K. Volety, Michael Savarese, S. Gregory Tolley, William S. Arnold, Patricia Sime, Patricia Goodman, Robert H. Chamberlain, Peter H. Doering

Journal:

Ecological Indicators

Year:

2009

Language:

english

File:

PDF, 892 KB

english, 2009

16

TGFβ and Smad3 link inflammation to progressive fibrosis

Jack Gauldie, Philippe Bonniaud, Peter Margetts, Patricia Sime, Kjetil Ask, Martin Kolb

Journal:

International Congress Series

Year:

2007

Language:

english

File:

PDF, 1.18 MB

english, 2007

17

Lymphatic filariasis in western Ethiopia with special emphasis on prevalence of Wuchereria bancrofti antigenaemia in and around onchocerciasis endemic areas

Welelta Shiferaw, Tadesse Kebede, Patricia M. Graves, Lemu Golasa, Teshome Gebre, Aryc W. Mosher, Abiot Tadesse, Heven Sime, Tariku Lambiyo, K.N. Panicker, Frank O. Richards, Asrat Hailu

Journal:

Transactions of the Royal Society of Tropical Medicine and Hygiene

Year:

2012

Language:

english

File:

PDF, 1.42 MB

english, 2012

18

Transfer of Tumor Necrosis Factor-α to Rat Lung Induces Severe Pulmonary Inflammation and Patchy Interstitial Fibrogenesis with Induction of Transforming Growth Factor-β1 and Myofibroblasts

Patricia J. Sime, Robert A. Marr, David Gauldie, Zhou Xing, Bryan R. Hewlett, Frank L. Graham, Jack Gauldie

Journal:

The American Journal of Pathology

Year:

1998

Language:

english

File:

PDF, 1.31 MB

english, 1998

19

Efficacy and safety of cholesterol-lowering treatment – Authors' reply

Colin Baigent, Anthony Keech, Patricia Kearney, Rory Collins, John Simes

Journal:

Year:

2006

Language:

english

File:

PDF, 48 KB

english, 2006

20

Statins and diabetes – Authors' reply

Patricia M Kearney, Anthony Keech, John Simes, Rory Collins, Colin Baigent

Journal:

Year:

2008

Language:

english

File:

PDF, 44 KB

english, 2008

21

Aryl Hydrocarbon Receptor-Deficient Mice Develop Heightened Inflammatory Responses to Cigarette Smoke and Endotoxin Associated with Rapid Loss of the Nuclear Factor-κB Component RelB

Thomas H. Thatcher, Sanjay B. Maggirwar, Carolyn J. Baglole, Heather F. Lakatos, Thomas A. Gasiewicz, Richard P. Phipps, Patricia J. Sime

Journal:

The American Journal of Pathology

Year:

2007

Language:

english

File:

PDF, 940 KB

english, 2007

22

Epithelium-specific adenoviral transfer of a dominant-negative mutant TGF-β type II receptor stimulates embryonic lung branching morphogenesis in culture and potentiates EGF and PDGF-AA

Jingsong Zhao, Patricia J. Sime, Pablo Bringas Jr., Jack Gauldie, David Warburton

Journal:

Mechanisms of Development

Year:

1998

Language:

english

File:

PDF, 898 KB

english, 1998

23

A new direction in the pathogenesis of idiopathic pulmonary fibrosis?

Jack Gauldie, Martin Kolb, Patricia J Sime

Journal:

Respiratory Research

Year:

2001

Language:

english

File:

PDF, 49 KB

english, 2001

24

Fibrosis of the Lung and Other Tissues: New Concepts in Pathogenesis and Treatment

Patricia J. Sime, Katherine M.A. O'Reilly

Journal:

Clinical Immunology

Year:

2001

Language:

english

File:

PDF, 267 KB

english, 2001

25

Adenovirus-Vector-Mediated Cytokine Gene Transfer to Lung Tissue

JACK GAULDIE, FRANK GRAHAM, ZHOU XING, TODD BRACIAK, RONAN FOLEY, PATRICIA J. SIME

Journal:

Annals of the New York Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 2.04 MB

english, 1996

26

The Triterpenoid CDDO-Me Inhibits Bleomycin-Induced Lung Inflammation and Fibrosis

Kulkarni, Ajit A., Thatcher, Thomas H., Hsiao, Hsi-Min, Olsen, Keith C., Kottmann, Robert Matthew, Morrissette, Jason, Wright, Terry W., Phipps, Richard P., Sime, Patricia J., Ryffel, Bernhard

Journal:

Year:

2013

Language:

english

File:

PDF, 2.30 MB

english, 2013

27

Inhibitory Effects of PPARγ Ligands on TGF-β1–Induced Corneal Myofibroblast Transformation

Jeon, Kye-Im, Kulkarni, Ajit, Woeller, Collynn F., Phipps, Richard P., Sime, Patricia J., Hindman, Holly B., Huxlin, Krystel R.

Journal:

The American Journal of Pathology

Year:

2014

Language:

english

File:

PDF, 2.95 MB

english, 2014

28

Matrix Biology of Idiopathic Pulmonary Fibrosis

Thannickal, Victor J., Henke, Craig A., Horowitz, Jeffrey C., Noble, Paul W., Roman, Jesse, Sime, Patricia J., Zhou, Yong, Wells, Rebecca G., White, Eric S., Tschumperlin, Daniel J.

Journal:

The American Journal of Pathology

Year:

2014

Language:

english

File:

PDF, 1.01 MB

english, 2014

29

Temporal separation of the dual effects of TGFB1 on epithelium: Early disruption in ion transport is followed by delayed increase in barrier function

Howe, Kathryn, Sime, Patricia, Gauldie, Jack, McKay, Derek M.

Journal:

Gastroenterology

Year:

2000

Language:

english

File:

PDF, 191 KB

english, 2000

30

OROPHARYNGEAL ASPIRATION OF A SILICA SUSPENSION PRODUCES A SUPERIOR MODEL OF SILICOSIS IN THE MOUSE WHEN COMPARED TO INTRATRACHEAL INSTILLATION

Lakatos, Heather F., Burgess, Heather A., Thatcher, Thomas H., Redonnet, Michelle R., Hernady, Eric, Williams, Jacqueline P., Sime, Patricia J.

Journal:

Experimental Lung Research

Year:

2006

Language:

english

File:

PDF, 2.45 MB

english, 2006

31

SENSITIVITY TO BLEOMYCIN-INDUCED LUNG INJURY IS NOT MODERATED BY AN ANTIGEN-LIMITED T-CELL REPERTOIRE

Thatcher, Thomas H., Sime, Patricia J., Barth, Richard K.

Journal:

Experimental Lung Research

Year:

2005

Language:

english

File:

PDF, 1.78 MB

english, 2005

32

Electrophilic Peroxisome Proliferator–Activated Receptor-γ Ligands Have Potent Antifibrotic Effects in Human Lung Fibroblasts

Ferguson, Heather E., Kulkarni, Ajit, Lehmann, Geniece M., Garcia-Bates, Tatiana M., Thatcher, Thomas H., Huxlin, Krystel R., Phipps, Richard P., Sime, Patricia J.

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2009

Language:

english

File:

PDF, 536 KB

english, 2009

33

Inhibition of Transglutaminase 2, a Novel Target for Pulmonary Fibrosis, by Two Small Electrophilic Molecules

Olsen, Keith C., Epa, Amali P., Kulkarni, Ajit A., Kottmann, R. Matthew, McCarthy, Claire E., Johnson, Gail V., Thatcher, Thomas H., Phipps, Richard P., Sime, Patricia J.

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2014

Language:

english

File:

PDF, 1.29 MB

english, 2014

34

Measuring Extracellular pH in a Lung Fibrosis Model with acidoCEST MRI

Jones, Kyle M., Randtke, Edward A., Howison, Christine M., Cárdenas-Rodríguez, Julio, Sime, Patricia J., Kottmann, Matthew R., Pagel, Mark D.

Journal:

Molecular Imaging and Biology

Year:

2015

Language:

english

File:

PDF, 1.04 MB

english, 2015

35

More Than Structural Cells, Fibroblasts Create and Orchestrate the Tumor Microenvironment

Baglole, Carolyn J., Ray, Denise M., Bernstein, Steven H., Feldon, Steven E., Smith, Terry J., Sime, Patricia J., Phipps, Richard P.

Journal:

Immunological Investigations

Year:

2006

Language:

english

File:

PDF, 365 KB

english, 2006

36

Ocular Fibroblast Diversity: Implications for Inflammation and Ocular Wound Healing

Xi, Xia, McMillan, David H., Lehmann, Geniece M., Sime, Patricia J., Libby, Richard T., Huxlin, Krystel R., Feldon, Steven E., Phipps, Richard P.

Journal:

Investigative Ophthalmology & Visual Science

Year:

2011

Language:

english

File:

PDF, 1.24 MB

english, 2011

37

A novel small-molecule MRCK inhibitor blocks cancer cell invasion

Unbekandt, Mathieu, Croft, Daniel R, Crighton, Diane, Mezna, Mokdad, McArthur, Duncan, McConnell, Patricia, Schüttelkopf, Alexander W, Belshaw, Simone, Pannifer, Andrew, Sime, Mairi, Bower, Justin, Dr

Journal:

Cell Communication and Signaling

Year:

2014

Language:

english

File:

PDF, 3.69 MB

english, 2014

38

Spiruchostatin A Inhibits Proliferation and Differentiation of Fibroblasts from Patients with Pulmonary Fibrosis

Davies, Elizabeth R., Haitchi, Hans Michael, Thatcher, Thomas H., Sime, Patricia J., Kottmann, R. Matthew, Ganesan, Arasu, Packham, Graham, O'Reilly, Katherine M. A., Davies, Donna E.

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2012

Language:

english

File:

PDF, 461 KB

english, 2012

39

Disruption of SIRT1-mediated Control of Circadian Molecular Clock and Inflammation in Chronic Obstructive Pulmonary Disease

Yao, Hongwei, Sundar, Isaac K, Huang, Yadi, Gerloff, Janice, Sellix, Michael T, Sime, Patricia J, Rahman, Irfan

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2015

Language:

english

File:

PDF, 1.94 MB

english, 2015

40

PPARs: Regulators and Translational Targets in the Lung

Reddy, Raju C., Rehan, Virender K., Roman, Jesse, Sime, Patricia J.

Journal:

Year:

2012

Language:

english

File:

PDF, 60 KB

english, 2012

41

Metabolomics in Lung Inflammation:A High-Resolution 1 H NMR Study of Mice Exposedto Silica Dust

Hu, Jian Zhi, Rommereim, Donald N., Minard, Kevin R., Woodstock, Angie, Harrer, Bruce J., Wind, Robert A., Phipps, Richard P., Sime, Patricia J.

Journal:

Toxicology Mechanisms and Methods

Year:

2008

Language:

english

File:

PDF, 2.87 MB

english, 2008

42

Emerging PPARγ-Independent Role of PPARγ Ligands in Lung Diseases

Kulkarni, Ajit A., Woeller, Collynn F., Thatcher, Thomas H., Ramon, Sesquile, Phipps, Richard P., Sime, Patricia J.

Journal:

Year:

2012

Language:

english

File:

PDF, 671 KB

english, 2012

43

The Role of PPARs in Lung Fibrosis

Lakatos, Heather F., Thatcher, Thomas H., Kottmann, R. Matthew, Garcia, Tatiana M., Phipps, Richard P., Sime, Patricia J.

Journal:

Year:

2007

Language:

english

File:

PDF, 631 KB

english, 2007

44

Electrophilic PPARγ Ligands Attenuate IL-1β and Silica-Induced Inflammatory Mediator Production in Human Lung Fibroblasts via a PPARγ-Independent Mechanism

Hogan, Christopher M., Thatcher, Thomas H., Sapinoro, Ramil E., Gurell, Michael N., Ferguson, Heather E., Pollock, Stephen J., Jones, Carolyn, Phipps, Richard P., Sime, Patricia J.

Journal:

Year:

2011

Language:

english

File:

PDF, 2.02 MB

english, 2011

45

Inhibitory effects of PPARγ ligands on TGF-β1-induced CTGF expression in cat corneal fibroblasts

Jeon, Kye-Im, Phipps, Richard P., Sime, Patricia J., Huxlin, Krystel R.

Journal:

Experimental Eye Research

Year:

2015

Language:

english

File:

PDF, 800 KB

english, 2015

46

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California - ()] D101. ANIMAL MODELS OF EMPHYSEMA - Genetic Ablation Of Activating Transcription Factor 3 Enhances The Susceptibility To Cigarette Smoke Induced Pulmonary Emphysema In Mice

Rangasamy, Tirumalai, Sivagnanalingam, Umayal, Mariani, Thomas, Gascon, Jody, Sime, Patricia J., Lunger, Valerie, Hai, Tsowin, Tuder, Rubin, Geoars, Steve N.

Year:

2012

Language:

english

File:

PDF, 18 KB

english, 2012

47

RelB Is Differentially Regulated by IκB Kinase-α in B Cells and Mouse Lung by Cigarette Smoke

Yang, Se-Ran, Yao, Hongwei, Rajendrasozhan, Saravanan, Chung, Sangwoon, Edirisinghe, Indika, Valvo, Samantha, Fromm, George, McCabe, Michael J., Sime, Patricia J., Phipps, Richard P., Li, Jian-Dong, B

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2009

Language:

english

File:

PDF, 1.49 MB

english, 2009

48

Reply: From Idiopathic Pulmonary Fibrosis to Cystic Fibrosis: Got Lactate?

Kottmann, Robert, Phipps, Richard, Sime, Patricia

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2013

Language:

english

File:

PDF, 73 KB

english, 2013

49

New Light Is Shed on the Enigmatic Origin of the Lung Myofibroblast

Rosas, Ivan O., Kottman, Robert M., Sime, Patricia J.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2013

Language:

english

File:

PDF, 56 KB

english, 2013

50

Transglutaminase 2 and Its Role in Pulmonary Fibrosis

Olsen, Keith C., Sapinoro, Ramil E., Kottmann, R. M., Kulkarni, Ajit A., Iismaa, Siiri E., Johnson, Gail V. W., Thatcher, Thomas H., Phipps, Richard P., Sime, Patricia J.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2011

Language:

english

File:

PDF, 1.82 MB

english, 2011

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